Table 3.

The Association between MTNR1B Variants and Adiposity adjusting for Insomnia

					Adiposity					Adiposity-Insomnia
SNPs	BP	A1	A2	MAF	p value	FDR p value	OR	LCI	UCI	p value	FDR p value	OR	LCI	UCI	Type of Mutation
rs12290860	92979012	G	A	0.2240	0.0042	0.0250	0.74	0.54	0.95	0.0012	0.0040	0.66	0.40	0.91	Intronic
rs61747139	92981951	A	G	0.2270	0.0042	0.0250	0.74	0.54	0.95	0.0013	0.0040	0.66	0.41	0.92	Missense
rs6483210	92981429	C	T	0.2270	0.0043	0.0250	0.75	0.54	0.95	0.0013	0.0040	0.66	0.41	0.92	Intronic
rs7127128	92980510	A	G	0.2270	0.0044	0.0250	0.75	0.54	0.95	0.0013	0.0040	0.66	0.41	0.92	Intronic
rs12292400	92979446	G	C	0.2250	0.0055	0.0250	0.75	0.55	0.95	0.0017	0.0047	0.67	0.41	0.92	Intronic
rs6483209	92976223	C	T	0.2120	0.0022	0.0250	0.73	0.52	0.93	0.0003	0.0025	0.62	0.36	0.88	Intronic
rs7130424	92980527	T	C	0.2660	0.0117	0.0281	0.79	0.60	0.97	0.0021	0.0053	0.70	0.46	0.93	Intronic
rs12272268	92975633	C	G	0.2520	0.0075	0.0250	0.77	0.58	0.96	0.0007	0.0040	0.67	0.43	0.91	Intronic
rs12792653	92982750	A	G	0.4460	0.0121	0.0281	0.81	0.64	0.97	0.0872	0.1313	0.83	0.62	1.04	3’-UTR
rs1562444	92982683	A	G	0.4460	0.0122	0.0281	0.81	0.64	0.98	0.0875	0.1313	0.83	0.62	1.04	3’-UTR
rs11020126	92973751	G	A	0.1810	0.0060	0.0250	0.73	0.51	0.96	0.000045	0.0012	0.56	0.27	0.84	Intronic
rs11020125	92973378	T	G	0.1710	0.0070	0.0250	0.74	0.51	0.96	0.0001	0.0012	0.57	0.28	0.86	Intronic
rs12277904	92978680	C	T	0.1370	0.0105	0.0281	0.73	0.48	0.97	0.0115	0.0203	0.68	0.38	0.98	Intronic
rs116625623	92971729	G	T	0.0950	0.0180	0.0385	0.70	0.41	1.00	0.0012	0.0040	0.54	0.17	0.92	Intronic
rs7129768	92980510	G	A	0.0880	0.0202	0.0404	0.70	0.40	1.00	0.0033	0.0075	0.56	0.18	0.95	Intronic
rs76371840	92971529	C	T	0.0740	0.0266	0.0499	1.48	1.13	1.82	0.0423	0.0705	1.54	1.12	1.96	Intronic
rs6483208	92972678	T	G	0.2200	0.0291	0.0514	0.80	0.60	1.00	0.0003	0.0025	0.63	0.38	0.89	Intronic
rs4388843	92971820	G	A	0.3110	0.2311	0.3015	0.90	0.72	1.08	0.0058	0.0123	0.73	0.50	0.95	Intronic
rs4601728	92971992	A	G	0.3130	0.2432	0.3040	0.90	0.72	1.08	0.0066	0.0132	0.73	0.51	0.96	Intronic
rs12804291	92972141	C	T	0.2650	0.2203	0.3005	0.89	0.71	1.08	0.0092	0.0172	0.73	0.50	0.97	Intronic

Adiposity for adjusted age, sex, and ancestry; Adiposity-Insomnia for Adiposity model with adjustment for Insomnia. The results of the associations are listed as Odds Ratio (OR) with the Lower and Upper Confidence Interval (LCI and UCI) and the corresponding adjusted False Discovery Rate (FDR) p value. A1 and A2 are reference allele and alternative allele; MAF is Minor Allele Frequency; BP is Base Pair