Table 1.
Disentanglement metrics for two splatter-simulated single-cell RNA-seq datasets with four ground truth variables
Spearman correlation gap | FactorVAE metric | MIG | ||
---|---|---|---|---|
Linear step | PCA | 0.68 0.00 | 0.35 0.01 | 0.54 0.00 |
VAE | 0.3 0.04 | 0.4 0.02 | 0.48 0.13 | |
-TCVAE | 0.18 0.05 | 0.48 0.03 | 0.72 0.02 | |
Non-linear step | PCA | 0.72 0.00 | 0.35 0.01 | 0.55 0.00 |
VAE | 0.27 0.07 | 0.41 0.02 | 0.43 0.08 | |
-TCVAE | 0.16 0.06 | 0.51 0.04 | 0.66 0.16 |
The mean and standard deviation over 5 runs are presented for each method. The dimensionality of the latent space was 10 for all three approaches