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. 2021 May 20;22:158. doi: 10.1186/s13059-021-02373-4

Table 1.

Disentanglement metrics for two splatter-simulated single-cell RNA-seq datasets with four ground truth variables

Spearman correlation gap FactorVAE metric MIG
Linear step PCA 0.68 0.00 0.35 0.01 0.54 0.00
VAE 0.3 0.04 0.4 0.02 0.48 0.13
-TCVAE 0.18 0.05 0.48 0.03 0.72 0.02
Non-linear step PCA 0.72 0.00 0.35 0.01 0.55 0.00
VAE 0.27 0.07 0.41 0.02 0.43 0.08
-TCVAE 0.16 0.06 0.51 0.04 0.66 0.16

The mean and standard deviation over 5 runs are presented for each method. The dimensionality of the latent space was 10 for all three approaches