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CCND1 was a target of miR-488.a The binding site between miR-488 and CCND1 3UTR. b The interaction between miR-488 and CCND1 was confirmed by dual-luciferase reporter assay. c The protein level of CCND1 in Cal-27 and SCC9 cells with miR-488 overexpression was detected by western blot. d The protein level of CCND1 in Cal-27 and SCC9 cells transfected with sh-circ_0000745#1+anti-NC, sh-NC+anti-NC or sh-circ_0000745#1+anti-miR-488 was detected by western blot. **P<0.01 and ***P<0.001
