Table 3.
Characteristics of patients with moderate to severe airflow limitation
| Patients with moderate to severe AFL (n=61) | |||||
|---|---|---|---|---|---|
| LAMA/LABA | LAMA | p value* | No-BD | p value** | |
| n=32 | n=22 | n=7 | |||
| Age | 72. 26.7 | 70.86.6 | 0.236 | 69.95.6 | 0.406 |
| Sex | 0.804 | 0.929 | |||
| Male | 27 (84.4) | 18 (81.8) | 6 (85.7) | ||
| Female | 5 (15.6) | 4 (18.2) | 1 (14.3) | ||
| Smoking status | 0.412 | 0.262 | |||
| Current smoker | 11 (34.4) | 10 (45.5) | 4 (57.1) | ||
| Ex-smoker | 21 (65.6) | 12 (54.5) | 3 (42.9) | ||
| Severity of AFL | 0.344 | 0.399 | |||
| Moderate | 29 (90.6) | 18 (81.8) | 7 (100) | ||
| Severe | 3 (9.4) | 4 (18.2) | 0 | ||
| Comorbidities | |||||
| Cardiovascular disease | 16 (50.0) | 13 (59.1) | 0.510 | 6 (85.7) | 0.084 |
| Diabetes mellitus | 6 (18.8) | 6 (27.3) | 0.459 | 3 (42.9) | 0.170 |
| Surgical procedure | 0.098 | 0.887 | |||
| Lobectomy | 26 (81.3) | 22 (100) | 6 (85.7) | ||
| Segmentectomy | 1 (3.1) | 0 | 0 | ||
| Partial resection | 5 (15.6) | 0 | 1 (14.3) | ||
| Pathologic staging | 0.016 | 0.148 | |||
| I | 26 (81.3) | 11 (50.0) | 4 (57.1) | ||
| II | 2 (6.3) | 8 (36.4) | 0 | ||
| III | 4 (12,5) | 3 (13.6) | 3 (42.9) | ||
| Adjuvant chemotherapy | 4 (12.5) | 5 (22.7) | 0.322 | 2 (28.6) | 0.286 |
| Recurrence (present) | 4 (12.5) | 10 (45.5) | 0.006 | 4 (57.1) | 0.008 |
| Treatment for recurrence | |||||
| Anticancer drug | 2 | 7 | 3 | ||
| Molecular targeted drug | 0 | 1 | 1 | ||
| None | 2 | 2 | 0 | ||
Data are presented as n (%) or as meanSD
COPD chronic obstructive pulmonary disease; LAMA long-acting muscarinic antagonists; LABA long-acting 2-agonists; BD bronchodilator; AFL airflow limitation