Table 4.
Univariate and multivariate analysis of favorable factors for postoperative prognosis in patients with moderate to severe AFL
| Clinicopathologic variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| RR | 95%CI | p value | RR | 95%CI | p value | |
| A. Analysis of favorable factors for overall survival | ||||||
| Age (<75year) | 0.88 | 0.292.25 | 0.798 | |||
| Histology: | 0.083 | |||||
| Squamous cell carcinoma | 1.00 | Reference | ||||
| Adenocarcinoma | 0.47 | 0.181.14 | 0.094 | |||
| Other | 0.18 | 0.011.01 | 0.051 | |||
| Lymph node metastasis (absent) | 0.61 | 0.261.55 | 0.290 | |||
| Pathologic stage: | 0.027 | 0.106 | ||||
| I | 1.00 | Reference | 1.00 | Reference | ||
| II | 2.96 | 0.998.25 | 0.052 | 2.14 | 0.706.16 | 0.176 |
| III | 3.66 | 1.2010.49 | 0.024 | 3.11 | 1.009.13 | 0.107 |
| Bronchodilator | 0.010 | 0.048 | ||||
| LAMA/LABA | 1.00 | Reference | 1.00 | Reference | ||
| LAMA or No-BD | 4.16 | 1.3711.1 | 3.21 | 1.0114.20 | ||
| B. Analysis of favorable factors for disease-free survival | ||||||
| Age (<75year) | 0.59 | 0.695.12 | 0.266 | |||
| Histology: | 0.038 | 0.350 | ||||
| Squamous cell carcinoma | 1.00 | Reference | 1.00 | Reference | ||
| Adenocarcinoma | 0.42 | 0.170.96 | 0.040 | 0.68 | 0.232.05 | 0.311 |
| Other | 0.16 | 0.010.90 | 0.035 | 0.23 | 0.011.59 | 0.148 |
| Lymph node metastasis (absent) | 0.49 | 0.221.13 | 0.091 | |||
| Pathologic stage | 0.007 | 0.233 | ||||
| I | 1.00 | Reference | 1.00 | Reference | ||
| II | 3.21 | 1.188.17 | 0.024 | 1.35 | 0.394.90 | 0.635 |
| III | 4.13 | 1.4711.0 | 0.009 | 2.70 | 0.838.37 | 0.278 |
| Bronchodilator | 0.003 | 0.018 | ||||
| LAMA/LABA | 1.00 | Reference | 1.00 | Reference | ||
| LAMA or No-BD | 3.90 | 1.5511.8 | 3.29 | 1.2210.43 | 0.120 | |
COPD chronic obstructive pulmonary disease; LAMA long-acting muscarinic antagonists; LABA long-acting 2-agonists; BD bronchodilator; RR relative risk; CI confidence interval