Table 1.
Patient characteristics in the four groups (n = 379)
| Characteristic | HC | TB | DM | TB+DM | P value |
|---|---|---|---|---|---|
| n = 133 | n = 113 | n = 59 | n = 74 | ||
| Sex (male/female) | 60/73 | 66/47 | 32/27 | 46/28 | 0.0497* |
| Age (years) | 45.417.2 | 47.017.8 | 59.614.0 | 58.112.5 | <0.0001* |
| BMI (kg/m2) | 20.92.1 | 21.12.4 | 20.01.9 | 20.62.2 | 0.0110* |
| HbA1c (%) | NAa | NA | 11.54.5 | 11.33.8 | 0.3915 |
| Fasting glucose | NA | NA | 13.35.5 | 12.33.7 | 0.2366 |
| Smoking history | NA | 48/113 (42.5%) | 20/59 (33.9%) | 38/74 (51.4%) | 0.1219 |
| TSPOT.TB (+) | NA | 96/110 (87.3%)b | NA | 42/74 (56.6%) | 0.5726 |
| DM medication | NA | NA | 59/59 (100.0%) | 50/74 (67.6%) | 0.0011* |
| Insulin | 10/59 (16.9%) | 5/50 (10.0%) | 0.0832 | ||
| Metformin | 42/59 (71.2%) | 43/50 (86.0%) | 0.5362 | ||
| Others | 7/59 (11.9%) | 2/50 (4.0%) | 0.1591 | ||
| Years since DM diagnose | NA | NA | |||
| <1 | 0/59 (0.0%) | 11/74 (14.9%) | 0.0006* | ||
| 1-5 | 21/59 (35.6%) | 32/74 (43.2%) | 0.0006* | ||
| 6-15 | 28/59 (47.5%) | 28/74 (37.8%) | 0.2695 | ||
| >15 | 10/59 (16.9%) | 3/74 (4.1%) | 0.0070* | ||
| With TB drug resistant | NA | 8/113 (7.1%) | NA | 2/74 (2.7%) | 0.1953 |
| With TB pulmonary cavity | NA | 32/113 (28.3%) | NA | 15/74(20.0%) | 0.2169 |
Different characteristic and statistic results among the four groups. HC Healthy community controls, TB Tuberculosis group, DM Diabetes group, TB+DM TB-DM co-morbidity group, BMI Body Mass Index, HbA1c Hemoglobin A1c, TSPOT.TB tuberculosis infectious T-lymphocyte spot assay; aNA not applicable; bData available from 96/110 patients. *Significant value (P < 0.05)