Table 2.
List of monoclonal antibodies currently in clinical trials for use against viruses.
| Virus | Monoclonal antibody | Clinical status | Refs/Clinicaltrials.gov ID |
|---|---|---|---|
| Influenza | VIS410 | Phase II | 42, 43; NCT02989194, NCT03040141 |
| MEDI8852 | Phase II | 40, 41; NCT02603952 | |
| Ebola | MAb114 | Phase I | NCT03478891 |
| Triple cocktail ZMapp | Phase I/II | NCT02363322 | |
| Triple antibody cocktail atoltivimab+odesivimab+maftivimab | FDA approved in October 2020 for EBOV | FDA.gov | |
| SARS-CoV-2 | Casirivimab+imdevimab | FDA EUA approval in November 2020 | FDA.gov |
| Bamlanivimab | FDA EUA approval in November 2020 | FDA.gov |