Table 3.

Foveal and parafoveal VD percentages of the superficial and deep capillary plexuses, FAZ measurements, and CC flow area values in the four quadrants in the early period and at 6 months in COVID-19 patients and healthy control subjects

Factor	Time of Study	Control Group (n = 25)	COVID-19 Group (n = 25)	p Value*
Parafoveal superficial superior VD (%)	Early period	51.82 ± 3.37	49.63 ± 4.98	0.01
	At 6 months		49.09 ± 4.54	0.0001
	p Value†		0.365
Parafoveal superficial inferior VD (%)	Early period	51.52 ± 4.00	49.89 ± 4.25	0.048
	At 6 months		48.92 ± 5.51	0.007
	p Value†		0.099
Parafoveal superficial nasal VD (%)	Early period	49.99 ± 4.01	47.47 ± 4.33	0.003
	At 6 months		47.2 ± 4.8	0.001
	p Value†		0.650
Parafoveal superficial temporal VD (%)	Early period	48.80 ± 4.18	47.16 ± 4.01	0.048
	At 6 months		46.92 ± 4.55	0.017
	p Value†		0.631
Parafoveal deep superior VD (%)	Early period	55.16 ± 3.70	52.31 ± 4.52	0.001
	At 6 months		52.83 ± 4.45	0.003
	p Value†		0.352
Parafoveal deep inferior VD (%)	Early period	54.44 ± 3.73	52.36 ± 4.44	0.011
	At 6 months		52.42 ± 4.98	0.016
	p Value†		0.911
Parafoveal deep nasal VD (%)	Early period	55.08 ± 3.89	53.07 ± 4.03	0.012
	At 6 months		54.05 ± 3.53	0.148
	p Value†		0.052
Parafoveal deep temporal VD (%)	Early period	54.78 ± 3.73	52.99 ± 3.72	0.018
	At 6 months		53.56 ± 4.3	0.068
	p Value†		0.336
Superficial foveal VD (%)	Early period	17.64 ± 5.51	17.43 ± 7.36	0.870
	At 6 months		17.03 ± 6.56	0.604
	p Value†		0.199
Deep foveal VD (%)	Early period	33.91 ± 7.03	32.09 ± 8.41	0.230
	At 6 months		32.55 ± 8.07	0.359
	p Value†		0.440
CC flow area (mm2)	Early period	2.08 ± 0.11	2.15 ± 0.23	0.059
	At 6 months		2.09 ± 0.13	0.872
	p Value†		0.044
FAZ (mm2)	Early period	0.29 ± 0.11	0.31 ± 0.13	0.283
	At 6 months		0.30 ± 0.12	0.514
	p Value†		0.442

Bolded p-values below 0.05 were considered statistically significant.

VD, vessel density; FAZ, foveal avascular zone; CC, choriocapillaris.

^⁎Independent t test.

^†Paired t test.