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. 2021 May 21;335:449–456. doi: 10.1016/j.jconrel.2021.05.024

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© 2021 Published by Elsevier B.V.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 6 — IgG1 and IgG2a levels in C57BL/6 mice vaccinated with LPX/RBD-mRNA via different injection routes (n = 6). The IgG subtypes in serum on day 30 were determined by ELISA. Statistical analyses were performed using GraphPad Prism 8.01 software. One-way analysis of variance (ANOVA) was used to assess the significance of differences among groups.