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. 2021 Jan 20;2(1):137–151. doi: 10.1093/ehjdh/ztab003

Table 5.

Beta-coefficients for selected variables in VCG + ECG-based models

Input variable Elastic net Lasso Adaptive Plugin
Age, years 0.220 0.287 0.321 0.037
Ever tobacco smoker (yes-no) 0.075 0.079 0.150
Hypertension (yes-no) 0.162 0.186 0.323
Diastolic blood pressure, mmHg −0.037 −0.010 −0.032
Peak QRS-T angle 0.102 0.154 0.192 0.005
Peak QRS elevation 0.019
Area SVG azimuth 0.018 0.001
Area T azimuth 0.081 0.100 0.214
P V1 amplitude, µV 0.017
P aVL duration, ms 0.004
P aVL intrinsicoid, ms 0.015 0.015 0.104
P V4 intrinsicoid, ms −0.011
Pprime III duration, ms 0.024 0.015 0.040
Pprime V4 duration, ms 0.027 0.027 0.048
Pprime aVF duration, ms 0.025 0.015 0.028
Pprime V6 area, µV*ms −0.008
Q V3 amplitude, µV 0.077 0.043 0.101
Q III amplitude, µV 0.066 0.076 0.144
Q aVF amplitude, µV 0.003
Q II duration, ms 0.039 0.037 0.102
Q V3 duration, ms 0.159 0.211 0.252 0.056
Q aVF duration, ms 0.042 0.030 0.018
Q I intrinsicoid, ms 0.022 0.066
Q aVF intrinsicoid, ms 0.043 0.054 0.015
Q V1 intrinsicoid, ms 0.029
Q aVL area, µV*ms 0.006
R V4 duration, ms 0.017 0.011 0.076
R aVL duration, ms 0.026 0.005
R V1 area, µV*ms 0.022 0.010
R V2 area, µV*ms 0.045 0.045 0.082
R V6 area, µV*ms 0.003
R III intrinsicoid, ms 0.044 0.042 0.056
R aVL intrinsicoid, ms 0.034 0.031 0.084
R aVF intrinsicoid, ms 0.051 0.047 0.153
R V6 intrinsicoid, ms 0.036 0.025 0.056
S V1 duration, ms −0.026 −0.018 −0.016
Rprime V4 amplitude, µV 0.055 0.066 0.115
Rprime I area, µV*ms 0.064 0.060 0.102
Rprime aVR area, µV*ms 0.046 0.037 0.073
Sprime V4 amplitude, µV 0.030 0.012 0.039
S prime V6 duration, ms −0.0005
Sprime V1 area, µV*ms 0.033 0.033 0.089
Sprime V6 area, µV*ms −0.005
Sprime V2 intrinsicoid, ms −0.038 −0.040 −0.193
J-point amplitude in lead I, µV −0.038
ST segment middle amplitude in aVR, µV 0.031
Maximum of ST amplitude in aVR, µV 0.024 0.012
Minimum of STJ and STM amplitudes in lead I, µV −0.074 −0.007
Minimum of ST amplitudes in lead I, µV −0.153 −0.241
Minimum of either T amplitude or T-ST aVL, µV −0.057 −0.081 −0.179
Peak-to-peak QRS complex amplitude II, µV −0.045 −0.033 −0.168
T aVL amplitude, µV −0.005
T area in lead I, µV*ms −0.026
T area in aVL, µV*ms −0.009
T V1 intrinsicoid, ms 0.028 0.025 0.079
T V2 intrinsicoid, ms 0.029 0.014 0.064
Tprime aVL amplitude, µV −0.008
Tprime aVF amplitude, µV 0.037 0.040 0.104
Tprime V1 area, µV*ms 0.031 0.027 0.097
Tprime V4 area, µV*ms −0.007
Tprime III area, µV*ms 0.022 0.014 0.061
Tprime aVL area, µV*ms −0.016 −0.014 −0.054
Tprime V2 intrinsicoid, ms 0.006
T and Tprime area in lead I, µV*ms −0.020
T and Tprime area in aVL, µV*ms −0.024
Peak of T > ST in aVL (yes-no) −0.004
ST depression V2 (yes-no) 0.001
ST depression V3 (yes-no) 0.034 0.033 0.033
ST depression V4 (yes-no) 0.020 0.007
ST elevation in lead I (yes-no) −0.004
ST elevation in lead V1 (yes-no) 0.004
ST elevation in lead V2 (yes-no) 0.038 0.031 0.088
ST elevation in lead V4 (yes-no) 0.0008
ST elevation in lead V6 (yes-no) −0.009
J point elevated by 100 μV in lead V1 (yes-no) −0.064 −0.065 −0.167
J point elevated by 100 μV in lead III (yes-no) −0.019 −0.115
J point elevated by 100 μV in lead aVF (yes-no) −0.019
Delta-wave was detected in lead III (yes-no) −0.022 −0.021 −0.058
Delta-wave was detected in aVL (yes-no) −0.040 −0.034 −0.157
ST J-point elevated in V1 (yes-no) −0.012 −0.003
ST J-point elevated in V2 (yes-no) −0.011 −0.011 −0.055
Frontal QRS-T angle, degrees 0.069 0.069 0.040 0.003
Constant −2.30 −2.31 −2.51 −4.92

STJ, end of QRS point amplitude; STM, middle of ST segment amplitude.