TABLE 2.

ATP-dependent proteases of selected bacterial and other species

Species	No. of encoded proteins	Lon	ClpX	ClpP	ClpA	ClpC	FtsH	HslUV
E. coli	4289	✓	✓	✓	✓	✓	✓	✓
B. subtilis	4100	✓	✓	✓	✓	✓	✓	✓
Mycobacterium tuberculosis	3918	✓	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	✓
Synechocystis	3169	✓	✓	✓	✓	✓	✓	×
Deinococcus radiodurans	2580	✓	✓	✓	✓	✓	✓	×
Thermotoga maritima	1846	✓	✓	✓	✓	✓	✓	✓
H. influenzae	1709	✓	✓	✓	×	×	✓	✓
Aquifex aeolicus	1522	✓	✓	✓	✓	✓	✓	✓
H. pylori 26695	1566	✓	✓	✓	✓	×	✓	✓
Treponema pallidum	1031	✓	✓	✓	✓	✓	✓	?
Chlamydia pneumoniae	1052	✓	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	×
Chlamydia trachomatis	894	✓	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	×
B. burgdorferi	850	✓ (Lon1 and Lon2)	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	✓
B. hermsii	827	✓ (Lon1 and Lon2)	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	✓
B. duttonii	850	✓ (Lon1 and Lon2)	✓	✓ (ClpP1 and ClpP2)	✓	✓	✓	✓
Rickettsia prowazekii	834	✓	✓	✓	×	×	✓	✓
Mycoplasma pneumoniae	677	✓	×	×	×	×	✓	×
Mycoplasma genitalium	467	✓	×	×	×	×	✓	×
N. gonorrhoeae	2030	✓	✓	✓	✓	×	✓	?
Caulobacter crescentus	3884	✓	✓	✓	✓	×	✓	✓
Y. pestis	3873	✓	✓	✓	✓	×	✓	✓
Streptococcus pyogenes	1680	✓	✓	✓	×	✓	✓	?
Staphylococcus epidermidis	2326	✓	✓	✓	×	✓	✓	✓
Listeria monocytogenes	2930	✓	✓	✓	✓	✓	✓	✓
Agrobacterium tumefaciens	5163	✓	✓	✓	✓	×	✓	✓
Clostridium tetani	2692	✓	✓	✓	✓	✓	✓	?
Arabidopsis thaliana	29085	✓	✓	✓	✓ limited homology	✓	✓	✓
Homo sapiens	∼21000	✓	✓	✓	✓ limited homology	×	✓	×