Overview of the major regions that generally make up IncI1-type plasmids as described by Sampei et al. (25). These regions include the plasmid replication and control regions, variable regions encoding antimicrobial resistance and/or virulence-associated genes, genes associated with plasmid stability and partitioning, the leading region, which may play a role in conjugal transfer, and regions associated with conjugal transfer (25). The plasmid represented is pSH1148_107, GenBank accession number JN983049 (43).