Table 3.
Univariable and multivariable linear regression analysis for the predictors of relative IGF-1 reduction (percent reduction after 6-month SRL treatment).
| Univariable linear regression analysis | |||||
|---|---|---|---|---|---|
| Dependent Variable | Independent Variables (IVs) | Adjusted R2 | B | β | p value |
| Relative IGF-1 reduction (%) | Age ≤40 yrs | 0.269 | -40.08 | -0.533 | <0.0001 |
| IGF-1 xULN | 0.091 | 6.985 | 0.330 | 0.018 | |
| T2-hypointense signal | 0.184 | 24.71 | 0.466 | 0.019 | |
| % GH reduction after OGTT | 0.069 | -0.187 | -0.315 | 0.079 | |
| OGTT paradox response | 0.071 | 22.158 | 0.317 | 0.077 | |
| Multivariable linear regression analysis | |||||
| Dependen Variable | Independent Variables (IVs) | Adjusted R2 | B | β | p value |
| Relative IGF-1 reduction (%) | All IVs | 0.695 | – | – | <0.0001 |
| Age ≤40 yrs | – | -46.927 | -0.654 | <0.0001 | |
| IGF-1 xULN | – | 7.278 | 0.303 | 0.019 | |
| T2-hypointense signal |
– | 13.735 | 0.259 | 0.043 | |
yrs, years; BMI, body mass index; IGF-1, insulin-like growth factor 1; ULN, upper limit of normality range; OGTT, oral glucose tolerance test.
Bold values are statistically significant (p-value ≤ 0.05).