TABLE 3.

RG fold change and stability parameters of the six tested RGs in PBMCs and CD4⁺ T cells^a

Condition	RG	Fold change
		Mean	Upper 90% CI	Lower 90% CI
PHA/DMSO
PBMC 24h	TBP	2.26	2.80	1.83
	RPL27A	1.97	2.33	1.66
	UBE2D2	2.95	3.87	2.26
	HPRT1	4.48	6.45	3.11
	YWHAZ	2.58	3.36	1.98
	GAPDH	8.54	13.58	5.37
CD4 24h	TBP	1.61	1.81	1.44
	RPL27A	1.66	1.96	1.40
	UBE2D2	2.37	2.64	2.12
	HPRT1	4.29	4.98	3.70
	YWHAZ	2.13	2.27	1.99
	GAPDH	8.15	9.71	6.84
VOR/DMSO
PBMC 24h	TBP	0.84	1.09	0.64
	RPL27A	1.14	1.47	0.89
	UBE2D2	0.95	1.23	0.73
	HPRT1	1.04	1.40	0.78
	YWHAZ	0.92	1.27	0.66
	GAPDH	1.19	1.59	0.89
CD4 24h	TBP	0.90	0.96	0.85
	RPL27A	1.02	1.11	0.94
	UBE2D2	1.10	1.24	0.97
	HPRT1	1.15	1.20	1.10
	YWHAZ	0.91	1.06	0.78
	GAPDH	1.56	1.68	1.45
STINGa/DMSO
PBMC 6h	TBP	0.61	0.69	0.54
	RPL27A	0.74	0.86	0.64
	UBE2D2	0.49	0.57	0.42
	HPRT1	0.70	0.82	0.60
	YWHAZ	0.39	0.48	0.31
	GAPDH	0.46	0.67	0.32
PBMC 24h	TBP	0.49	0.62	0.39
	RPL27A	0.53	0.64	0.44
	UBE2D2	0.46	0.58	0.37
	HPRT1	0.44	0.54	0.36
	YWHAZ	0.50	0.65	0.38
	GAPDH	0.37	0.46	0.30

^aRelated to Fig. 6B to E, G, and H. RG fold change expressed as average and 90% CI upper and lower limits under LRA conditions relative to that in DMSO in PBMCs (n = 7) and CD4⁺ T cells (n = 7) under PHA and VOR conditions after 24 h and in PBMCs (n = 8) under STINGa condition after 6 h and 24 h. Fold change of >2 or <0.5 highlighted in boldface font.