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ADCs measured in gray matter ROI in patients with CJD (white bars) are significantly lower (14% on average) than ADCs in the corresponding ROI of control patients (shaded bars) in all areas including both commonly affected areas of the frontal lobes (SFG) and parietal lobes (SMG) and typically spared frontal (PMC) and parietal (PSC) Rolandic cortex (individual ROI P value, 0.001–0.05).
