Fig 2.

Coronal SS-FSE T2-weighted image at gestational week 23 demonstrates a multilayered pattern. The deepest layer is low in signal intensity and represents the germinal matrix (arrowhead). Immediately superficial to the germinal matrix is a hyperintense layer that represents the periventricular zone (arrow). Immediately superficial to the periventricular zone is a hypointense layer that represents the subventricular and intermediate zones (double arrows). Superficial to this hypointense layer is a band of high signal intensity that represents the subplate (double arrowheads). The most superficial layer of the developing brain represents the developing cortex and marginal zone and is isointense to the germinal matrix (triple arrows).