Table 5.
Mean pain scores in subjects enrolled in BRUISE CONTROL 1 and 2 trials
| Average post-operative pain |
Most severe post-operative pain |
Post-operative pain on day of follow-up |
||||
|---|---|---|---|---|---|---|
| Variables | Mean (± SD) | P value (comparison with absence) | Mean ( ± SD) | P value (comparison with absence) | Mean (± SD) | P value (comparison with absence) |
| CSH | 3.8 ± 2.2 | <0.0001 | 6.1 ± 3.1 | <0.0001 | 2.4 ± 2.2 | 0.0001 |
| De novo surgery | 2.7 ± 2.2 | <0.0001 | 4.5 ± 3.0 | <0.0001 | 1.7 ± 2.0 | <0.0001 |
| Female sex | 2.8 ± 2.3 | 0.0005 | 4.5 ± 3.1 | 0.0009 | 1.8 ± 2.3 | 0.0002 |
| Age <65 years | 3.2 ± 2.2 | <0.0001 | 5.2 ± 2.8 | <0.0001 | 1.8 ± 1.9 | 0.02 |
| BMI <20 kg/m2 | 3.2 ± 2.4 | 0.01 | 5.2 ± 3.4 | 0.02 | Not associateda | Not associateda |
| Overall pain score for all 1308 patients in BC-1 and BC-2 (mean ± SD) | 2.4 ± 2.1 | 4.1 ± 3 | 1.5 ± 2.0 | |||
The models are dichotomized for moderate to severe post-operative pain (>4) vs. mild post-operative pain (0–3).
BMI, body mass index; CSH, clinically significant haematoma; ICD, implantable cardioverter-defibrillator; NS, not significant.
a
Post-operative pain on day of follow-up was not significantly different between subjects with BMI <20 kg/m2 and those with BMI ≥20 kg/m2 and are not being presented.