Appendix 2—figure 1. Scaling behavior of unconfined chromatin chains in good and poor solvent.

(a) LJ potential as a function of the distance between two beads, with snapshot of simulations of chromatin chain having 500 beads. Snapshots show unconfined, self-avoiding chromatin in good solvent conditions for a cutoff distance $r_c=2^{1/6}=1.1225$ (green) and self-attractive chromatin in poor solvent conditions, for a cutoff distance $r_c=2.5$. (b) Radius of gyration $Rg$ vs. the number of beads $N$ is calculated from the simulations of unconfined chromatin chain having $N=100,\mathrm{\dots }100,000$ beads (green and red dots). The green and red lines are guides to the eye. They can be fit with the power laws shown, demonstrating the polymeric scaling in the unconfined case for both good and poor solvent conditions.