Figure 4. Variation of the chromatin concentration profile as a function of the chromatin volume fraction.

Left panel: Chromatin concentrations are shown for different volume fractions of chromatin, $\varphi$. Right panel: The local volume fraction profiles show peripheral organization for $\varphi =0.3$ and $\varphi =0.1$ but not for $\varphi =0.5$. This demonstrates the transition from peripheral to conventional chromatin organization as the nucleus is dehydrated and $\varphi$ is increased.