Passive parameters |
Input conductance Gin
|
1 nS |
Same |
Input capacitance Cin
|
13 pF (E12.5, Figures 7B, C, D, F and 8B– D) or 18 pF (E14.5, Figure 7G) |
13 pF |
Resting potential Vr
|
−60 mV |
Same |
Injected current I
|
20 pA (Figure 7B–G) |
10 pA (Figure 8C) or 12 pA (Figure 8D) variable in Figure 8B
|
Transient sodium current Inat |
Maximal conductance GNat
|
20 nS |
Same |
Reversal potential ENa
|
60 mV |
Activation exponent |
3 |
Mid-activation Vm
|
−26 mV |
Steepness of activation km
|
9.5 mV |
Activation time constant |
1.5 ms |
Mid-inactivation Vh
|
−45 mV |
Steepness of inactivation Kh
|
−5 mV |
Inactivation time constant τm
|
Voltage-dependent (see Material s and methods) |
Persistent sodium current INap |
Maximal conductance |
Variable (see text and figure captions) |
Same |
Mid-activation voltage |
−36 mV |
Same |
Mid-inactivation Vs
|
|
−30 mV |
Steepness of inactivation ks
|
−5 mV |
Inactivation time constant |
Slow inactivation not included |
2 s |
Delayed rectifier potassium current IKdr |
Maximal conductance GKdr
|
Variable (see text and figure captions) |
Same |
Reversal potential EK
|
−96 mV |
Activation exponent |
3 |
Mid-activation Vn
|
−20 mV |
Steepness of activation kn
|
15 mV |
Activation time constant τm
|
10 ms |
Potassium A current IA (when included in the basic model) |
Maximal conductance GA
|
Equal to GKdr
|
Never included |
Mid-activation VmA
|
−30 mV |
Steepness of activation kmA
|
12 mV |
Activation time constant |
Instantaneous activation |
Mid-inactivation VhA
|
−70 mV |
Steepness of inactivation khA
|
−7 mV |
Inactivation time constant τhA
|
23 ms |