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. 2021 Jan 6;44(3):956–964. doi: 10.1007/s10753-020-01390-y

Table 1.

Non-Pregnant and Pregnant Mice Brain nNOS, NF-kB, And IL-6 At Basal State, Following Inflammation With Or Without Progesterone Pretreatment

Brain cytokine Group Mean (u) Standard deviation p value compared to LPS p value compared to non-pregnant
nNOS Non-pregnant Control 0.09 0.01 0.01 >
LPS 0.23 0.01
LPS + P 0.17 0.01 0.01 >
Pregnant Control 0.11 0.01 0.01 > 0.06
LPS 0.24 0.01 0.38
LPS + P 0.18 0.01 0.01 > 0.13
NF-kB Non-pregnant Control 0.11 0.01 0.01 >
LPS 0.19 0.01
LPS + P 0.16 0.01 0.01 >
Pregnant Control 0.12 0.01 0.01 > 0.05 >
LPS 0.22 0.02 0.05 >
LPS + P 0.12 0.01 0.01 > 0.01 >
IL-6 Non-pregnant Control 0.1 0.01 0.05 >
LPS 0.16 0.03
LPS + P 0.14 0.01 0.56
Pregnant Control 0.09 0.01 0.01 > 0.1
LPS 0.25 0.02 0.05 >
LPS + P 0.13 0.01 0.01 > 0.23

LPS, lipopolysaccharide, P, progesterone