Table 2.
Non-Pregnant And Pregnant Mice Brain IMCs And Microglial Activity At Basal State, Following Inflammation With Or Without Progesterone Pretreatment
| Brain immune system cells | Group | Mean (%) | Standard deviation | p value compered to LPS | p value compered to non-pregnant | |
|---|---|---|---|---|---|---|
| IMCs | Non-pregnant | Control | 24.7 | 8.07 | 0.01 > | |
| LPS | 67.8 | 7.45 | ||||
| LPS + P | 48.6 | 4.94 | 0.05 > | |||
| Pregnant | Control | 32.46 | 4.78 | 0.07 | 0.19 | |
| LPS | 38.86 | 4.07 | 0.01 > | |||
| LPS + P | 31.96 | 2.79 | 0.06 | 0.05 > | ||
|
Microglia Median (CD45) |
Non-pregnant | Control | 801.33 | 20.8 | 0.01 > | |
| LPS | 1023.66 | 22.95 | ||||
| LPS + P | 920 | 53.23 | 0.06 | |||
| Pregnant | Control | 634.33 | 13.67 | 0.01 > | 0.01 > | |
| LPS | 905.66 | 34.39 | 0.01 > | |||
| LPS + P | 808 | 31.02 | 0.05 > | 0.06 | ||
IMC, immature myeloid cells; LPS, lipopolysaccharide; P, progesterone