Table 2.
MUC5AC expression and tumor phenotype
| N | Negative (%) | Weak (%) | Moderate (%) | Strong (%) | p | ||
|---|---|---|---|---|---|---|---|
| MUC5AC staining in all cancers | |||||||
| Tumor stage | 0.3387 | ||||||
| pT1 | 70 | 87.1 | 8.6 | 1.4 | 2.9 | ||
| pT2 | 336 | 83.6 | 5.1 | 5.1 | 6.3 | ||
| pT3 | 907 | 85.7 | 5.8 | 3.0 | 5.5 | ||
| pT4 | 338 | 81.7 | 5.9 | 5.0 | 7.4 | ||
| Lymph node status | 0.4523 | ||||||
| pN− | 852 | 84.0 | 5.5 | 3.6 | 6.8 | ||
| pN + | 782 | 85.0 | 6.0 | 4.0 | 5.0 | ||
| Side | < 0.0001 | ||||||
| Left | 1204 | 88.0 | 4.7 | 2.5 | 4.8 | ||
| Right | 457 | 74.8 | 8.8 | 7.2 | 9.2 | ||
| Mismatch repair status | < 0.0001 | ||||||
| Deficient | 84 | 57.1 | 7.1 | 9.5 | 26.2 | ||
| Proficient | 1136 | 88.3 | 5.7 | 2.5 | 3.5 | ||
| MUC5AC in mismatch repair deficient cancers | |||||||
| Tumor stage | 0.0793 | ||||||
| pT1 | 6 | 83.3 | 0 | 0 | 16.7 | ||
| pT2 | 19 | 36.8 | 10.5 | 26.3 | 26.3 | ||
| pT3 | 40 | 52.5 | 7.5 | 7.5 | 32.5 | ||
| pT4 | 19 | 78.9 | 5.3 | 0 | 15.8 | ||
| Lymph node status | 0.0581 | ||||||
| pN− | 55 | 52.7 | 5.4 | 14.5 | 27.7 | ||
| pN + | 27 | 63.0 | 11.1 | 0 | 25.9 | ||
| MUC5AC in mismatch repair proficient cancers | |||||||
| Tumor stage | 0.0688 | ||||||
| pT1 | 45 | 88.9 | 11.1 | 0 | 0 | ||
| pT2 | 240 | 91.3 | 5.0 | 2.5 | 1.3 | ||
| pT3 | 618 | 88.7 | 5.5 | 2.1 | 3.7 | ||
| pT4 | 222 | 85.1 | 5.8 | 3.6 | 5.4 | ||
| Lymph node status | 0.7912 | ||||||
| pN− | 574 | 89.4 | 5.2 | 2.1 | 3.3 | ||
| pN + | 541 | 87.6 | 6.1 | 2.7 | 3.5 | ||