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. 2021 May 17;14:2177–2188. doi: 10.2147/DMSO.S311388

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© 2021 Zhou et al.

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Effects of microbial interactions on the Akkermansia–MetS association. (A) Associations of MetS and its components with 3 Akkermansia OTUs. (B) Groups of iOTUs according to their effects on the Akkermansia–MetS association. Interactions were visualized by changes in the protective effect of Akkermansia against MetS (ORs) when the abundance of iOTUs increased from Q1 to Q5. ORs were estimated by logistic regression in which the abundance of Akkermansia was treated as a continuous variable. (C) Annotation of iOTUs at the family and genus levels. β and FDR were estimated with the multivariate linear regression. Equation: .

Inline graphic — Effects of microbial interactions on the Akkermansia–MetS association. (A) Associations of MetS and its components with 3 Akkermansia OTUs. (B) Groups of iOTUs according to their effects on the Akkermansia–MetS association. Interactions were visualized by changes in the protective effect of Akkermansia against MetS (ORs) when the abundance of iOTUs increased from Q1 to Q5. ORs were estimated by logistic regression in which the abundance of Akkermansia was treated as a continuous variable. (C) Annotation of iOTUs at the family and genus levels. β and FDR were estimated with the multivariate linear regression. Equation: .