Table 1.
Characteristics of Participants According to Quintile of Akkermansia Abundance (n=6896)
| Characteristics | Q1 | Q2 | Q3 | Q4 | Q5 | P for Trend |
|---|---|---|---|---|---|---|
| n | 1379 | 1379 | 1379 | 1379 | 1380 | |
| Akkermansiaa, (%) | 0.02 (0.02–0.03) | 0.04 (0.04–0.05) | 0.08 (0.06–0.09) | 0.20 (0.15–0.33) | 7.05 (2.04–18.93) | |
| Age, years, mean(sd) | 53.6 (14.5) | 53.7 (14.6) | 52.0 (14.5) | 51.4 (14.6) | 52.9 (15.0) | < 0.001 |
| Sex, male, n (%) | 621 (45.0) | 623 (45.2) | 653 (47.4) | 661 (47.9) | 535 (38.7) | 0.02 |
| MetS, n (%) | 263 (19.1) | 288 (20.9) | 326 (23.6) | 303 (22.0) | 224 (16.23)** | 0.18 |
| Central obesity, n (%) | 341 (24.7) | 330 (23.9) | 370 (26.8) | 341 (24.7) | 259 (18.8)** | < 0.001 |
| Hyperglycemia, n (%) | 225 (16.3) | 262 (19.0) | 274 (19.9) | 252 (18.3) | 234 (16.9)** | 0.86 |
| Hypertension, n (%) | 712 (51.6) | 739 (53.5) | 703 (51.0) | 694 (50.3) | 638 (46.2) | < 0.001 |
| Hypertriglyceridemia, n (%) | 300 (21.8) | 328 (23.8) | 366 (26.5) | 396 (28.7) | 243 (17.3)** | 0.35 |
| Low HDL, n (%) | 376 (27.3) | 401 (29.1) | 417 (30.2) | 434 (31.5) | 356 (25.8)** | 0.88 |
Notes: aMedian (interquartile range) relative abundances of Akkermansia. **Data of Q5 was significantly different from those of Q1, Q2, Q3 and Q4 (P < 0.001).