Table 2.
Risks of MetS and Its Components in Subjects with Higher Akkermansia Compared to Those with Lower Akkermansia (or, 95% CI)a
| MetS | Central Obesity | Hyperglycemia | Hypertension | Hypertriglyceridemia | Low HDL | |
|---|---|---|---|---|---|---|
| Cutoff = 0.1b | ||||||
| Prevalence (%) Akk<0.1/Akk≥0.1 c | 20.9/19.6 | 25.2/21.9 | 18.2/17.9 | 52.2/48.4 | 23.5/23.8 | 28.7/28.9 |
| Model 1 | 0.99 (0.98–1.02) | 0.97 (0.95–0.99) | 0.99 (0.98–1.01) | 0.96 (0.94–0.99) | 1.00 (0.98–1.02) | 1.00 (0.98–1.02) |
| Model 2 | 0.99 (0.97–1.01) | 0.97 (0.95–0.99) | 1.00 (0.98–1.02) | 0.98 (0.99–1.00) | 1.00 (0.99–1.02) | 1.00 (0.98–1.03) |
| Model 3 | 1.00 (0.98–1.02) | 0.98 (0.95–1.00) | 1.00 (0.97–1.01) | 1.01 (0.99–1.04) | 1.00 (0.98–1.04) | 1.00 (0.97–1.02) |
| Cutoff = 0.2 | ||||||
| Prevalence (%) Akk<0.2/Akk≥0.2 c | 21.7/17.3 | 25.5/19.9 | 18.6/17.9 | 52.1/48.9 | 24.9/20.7 | 29.6/26.9 |
| Model 1 | 0.96 (0.94–0.98) | 0.94 (0.92–0.96) | 0.98 (0.96–1.00) | 0.95 (0.92–0.97) | 0.96 (0.93–0.98) | 0.97 (0.95–1.00) |
| Model 2 | 0.96 (0.94–0.98) | 0.94 (0.93–0.97) | 0.99 (0.97–1.00) | 0.96 (0.94–0.98) | 0.96 (0.94–0.98) | 0.98 (0.95–1.00) |
| Model 3 | 0.98 (0.95–1.00) | 0.96 (0.93–0.99) | 0.97 (0.95–1.00) | 0.98 (0.95–1.00) | 0.97 (0.94–0.99) | 0.98 (0.94–1.00) |
Notes: aModel 1 was the crude model; Model 2 was additionally adjusted for age and sex; Model 3 was additionally adjusted for geographic locations, and annual income. OR, odds ratio. 95% CI, 95% confidence interval. bThe cutoff values of Akkermansia (%) according to the non-linear models. cSubjects were divided into 2 groups according to the cutoff abundance of Akkermansia.