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. 2021 May 21;11:10717. doi: 10.1038/s41598-021-89831-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Lb21 but not Lb23 increases MRSA tolerance in C. elegans. (a) Survival of rrf-3(pk1426) mutants pretreated with Lb21, Lb23 and OP50 for 48 h before being shifted to MRSA strain 43484. (b) Survival of rrf-3(pk1426) mutants pretreated with Lb21, Lb23 and OP50 for 48 h before being shifted to MRSA strain 64. (c) Survival of rrf-3(pk1426) mutants after pretreatment with Lb21, Lb23 and OP50 for 48 h before being challenged with the pathogen ETEC F18. Graphs show a representative experiment from several independent experiments. See Table S1 for mean ± SD and log-rank test significance. (d) CFU level on day 6 of Lb21, Lb23 or OP50 and MRSA 43484 in rrf-3(pk1426) mutants pretreated for 48 h with Lb21, LB23 or OP50, respectively (3 technical replicates, n = 10 animals pr. group).