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. 2021 May 21;11:10664. doi: 10.1038/s41598-021-88982-2

Table 1.

β-Gal activity of each clinicopathological factor.

Variables (n = 89) n β-Gal activity p-value
Sex Male 68 0.181(0.002–0.516) 0.546
Female 21 0.181(0.034–0.444)
Age (years)  < 75 55 0.175(0.002–0.516) 0.057
 ≥ 75 34 0.191(0.111–0.463)
Preoperative BMI (kg/m2)  < 25 67 0.179(0.034–0.463) 0.816
 ≥ 25 22 0.183(0.002–0.516)
Preoperative Hb (g/dl)  < 12.0 29 0.188(0.111–0.463) 0.129
 ≥ 12.0 60 0.175(0.002–0.516)
Preoperative albumin (g/dl)  < 4.0 36 0.186(0.104–0.463) 0.237
 ≥ 4.0 53 0.176(0.002–0.516)
Preoperative CRP (mg/dl)  < 0.3 71 0.181(0.002–0.463) 0.818
 ≥ 0.3 18 0.175(0.104–0.516)
Preoperative CEA (ng/dl)  < 5.0 53 0.179(0.002–0.463) 0.637
 ≥ 5.0 36 0.184(0.093–0.516)
Preoperative CA19-9 (U/ml)  < 37 75 0.182(0.002–0.516) 0.723
 ≥ 37 14 0.173(0.121–0.463)
NAC  −  82 0.182(0.002–0.516) 0.154
 +  7 0.161(0.104–0.272)
pT 1–2 31 0.182(0.002–0.516) 0.483
3–4 58 0.178(0.034–0.463)
pN  −  23 0.188(0.104–0.456) 0.407
 +  66 0.178(0.002–0.516)
ly  −  15 0.188(0.115–0.463) 0.453
 +  74 0.180(0.002–0.516)
v  −  17 0.182(0.115–0.456) 0.635
 +  72 0.180(0.002–0.516)
Histological type dif 50 0.184(0.002–0.463) 0.435
undif 39 0.175(0.104–0.516)

Values of p were obtained by Wilcoxon test. BMI body mass index, CRP C-reactive protein, CEA Carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, NAC neoadjuvant chemotherapy, dif differentiated, undif undifferentiated.