Table 3.
Comparison of outcomes of deep brain stimulation in the subthalamic nucleus versus globus pallidus internus
| Outcomes | GPi | STN |
|---|---|---|
| Bradykinesia | + + | + + |
| Rigidity | + + | + + |
| Tremor | + + | + + |
| Quality of life | + + | + + |
| Dyskinesia reduction | + + | + |
| Stimulation-induced dyskinesia | − | −− |
| Medication reduction | + + | |
| Flexibility of long-term medication adjustments | + + | |
| Cognitive adverse effects | − | −− |
| Mood adverse effects | − | −− |
| Gait adverse effects | − | −− |
| Speech and swallowing adverse effects | − | −− |
| Ease of programming | + + | |
| Reduced battery consumption | + + | |
| Ability to use one lead | + + |
+ slight benefit; ++ clear benefit; − rarely occurring; −− more commonly occurring