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. 2021 May 21;4:603. doi: 10.1038/s42003-021-02129-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Representative average z-projections of the olfactory bulb that were immune-stained for eGFP (green, CF488) and pERK (magenta, CF 594). Scale bar, 50 µm valid for all images in the same panel. a VPCs following water, urine, or rat stimulation. Arrows indicate cells that are double-labeled for eGFP and pERK. b pERK⁺ MCs. c Averaged fraction of pERK⁺ VPCs of all VPCs in different stimulation groups (%). One-way ANOVA, LSD for single comparison, *p < 0.05 rat vs. water. d Cumulative probability of averaged fraction pERK⁺ VPCs of all VPCs in different stimulation groups (%). e Averaged number of pERK⁺ MCs per section in different stimulation groups. One-way ANOVA, LSD for single comparison, *p < 0.05 rat vs. water and rat vs. urine. Data are presented as box-plots including first, median, and third quartiles with whiskers representing the range of data points and distribution of single data points. n = 10 rats (water), n = 9 rats (urine), n = 10 rats (rat).