Table 1.

Statistical results of the investigated SNP.

Gene	SNP Alleles	Genotype p-value	Genotype adjust p (FDR)	Allele p-value	Allele adjust p	OR (95% CI)	Dominant model adjust p (p-value)	OR (95% CI)	Recessive model adjust p (p-value)	OR (95% CI)
SIRT1	rs12778366 C > T	0.4671	0.519	0.2889	0.3611	0.787 (0.505–1.226)	0.4574 (0.4117)	1.229 (0.751–2.012)	0.728 (0.2715)	0.407 (0.078–2.127)
	rs3758391 T > C	0.9332	0.09332	0.8402	0.8402	0.967 (0.695–1.344)	0.756 (0.756)	0.935 (0.614–1.425)	0.933 (0.9227)	0.963 (0.450–2.061)
	rs3740051 A > G	0.0674	0.2269	0.0212	0.0832	0.445 (0.220–0.901)	0.0809 (0.0263)	0.445 (0.215–0.922)	0.728 (0.3083)	3.123 (0.126–77.196)
	rs3818292 A > G	0.0341	0.2269	0.009783	0.0832	0.409 (0.204–0.822)	0.0809 (0.01176)	0.406 (0.198–0.833)	0.728 (0.3083)	3.123(0.126–77.196)
SIRT2	rs10410544 C > T	0.2355	0.2944	0.3382	0.3758	0.865 (0.642–1.165)	0.1466 (0.1173)	0.689 (0.432–1.099)	0.9329 (0.9329)	0.979 (0.591–1.620)
SIRT6	rs350843 A > C	0.1206	0.2269	0.0453	0.0880	1.613 (1.007–2.643)	0.0809 (0.04056)	1.719 (1.020–2.897)	0.728 (0.5824)	0.515 (0.046–5.729)
	rs350844 A > G	0.132	0.2269	0.05113	0.0880	1.593 (0.995–2.552)	0.0809 (0.04534)	1.680 (1.008–2.801)	0.728 (0.5824)	0.515 (0.046–5.729)
	rs107251 T > C	0.1588	0.2269	0.06163	0.0880	1.574 (0.975–2.539)	0.0809 (0.05662)	1.650 (0.983–2.770)	0.728 (0.5824)	0.515 (0.046–5.729)
	rs350845 A > G	0.1588	0.2269	0.06163	0.0880	1.574 (0.975–2.539)	0.0809 (0.05662)	1.650 (0.983–2.770	0.728 (0.5824)	0.515 (0.046–5.729)
	rs350846 C > G	0.06889	0.2269	0.02496	0.0832	1.734 (1.067–2.818)	0.0809 (0.02096)	1.846 (1.093–3.120)	0.728 (0.5824)	0.515 (0.046–5.729)

OR odds ratio, CI confidence interval.

Marginal associations with PD risk are indicated in bold.