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Haplotype frequencies in PD cases and controls.
| Haplotype | PD case (freq) | Control (freq) | Chi | p-value | Adjust p |
|---|---|---|---|---|---|
| SIRT1 | |||||
| CAA | 0.720 | 0.709 | 0.107 | 0.744 | 0.743 |
| TAA | 0.246 | 0.209 | 1.339 | 0.247 | 0.309 |
| TGG | 0.034 | 0.070 | 4.667 | 0.0307 | 0.0767 |
| SIRT6 | |||||
| CGCGG | 0.856 | 0.903 | 3.709 | 0.0541 | 0.090 |
| AATAC | 0.136 | 0.082 | 5.161 | 0.0231 | 0.0767 |
Haplotype block 1 is identified by rs3758391–rs3740051–rs3818292 in SIRT1 gene, and haplotype block 2 is identified by rs350843–rs350844–rs107251–rs350845–rs350846 in SIRT6 gene.
