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Top genes across all tissues from the ACT TWAS.
| Gene | Z-scorea | P value | Tissue |
|---|---|---|---|
| GDF5 | −4.30 | 1.70 × 10−5 | Adipose - subcutaneous |
| FRS2 | 4.07 | 4.67 × 10−5 | Pancreas |
| HDDC2 | 4.01 | 6.08 × 10−5 | Brain - cortex |
| EEF1B2 | −3.97 | 7.24 × 10−5 | Vagina |
aRepresents the number of standard deviations the mean expression of the gene in ACT cases is from that of controls, after adjusting for the weight of each eQTL influencing expression of the gene.
