Table 2.
Predictors of no follow‐up visit and attrition during Year 1, Years 2 to 4 and Years 5 to 10 following ART initiation among HIV‐positive adults in West Africa. IeDEA West‐Africa collaboration, 2002 to 2018
| No follow‐up (n = 71,283) |
Year 1 (n = 56,811 PY = 50,375) |
Years 2 to 4 (n = 51,985 PY = 129,348) |
Years 5 to 10 (n = 37,204 PY = 130,284) |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | ORa [IC 95%] | p‐value | PY | IR/100 PY | HRa [IC 95%] | p‐value | PY | IR/100 PY | HRa [IC 95%] | p‐value | PY | IR/100 PY | HRa [IC 95%] | p‐value | ||
| Sex | <0.001 | <0.001 | <0.001 | 0.016 | |||||||||||||
| Men | 24390 | 5.1 | 1.25 [1.15; 1.35] | 16498 | 22.6 | 1.22 [1.17; 1.27] | 41930 | 10.3 | 1.08[1.04; 1.12] | 41621 | 11.9 | 1.05[1.01; 1.08] | |||||
| Women | 46893 | 4.0 | 1 | 33877 | 17.5 | 1 | 87418 | 08.9 | 1 | 88663 | 10.3 | 1 | |||||
| Age at baseline | <0.020 | <0.001 | <0.001 | 0.001 | |||||||||||||
| <30 years | 16334 | 4.0 | 1 | 11497 | 20.1 | 1 | 29141 | 10.7 | 1 | 29517 | 12.7 | 1 | |||||
| 30 to 40 years | 29037 | 4.2 | 0.88 [0.79; 0.97] | 20745 | 18.3 | 0.87 [0.83; 092] | 53689 | 08.9 | 0.84 [0.80; 0.87] | 55297 | 10.4 | 0.90 [0.86; 0.94] | |||||
| >40 years | 25912 | 4.8 | 0.87 [0.78; 0.96] | 18133 | 19.6 | 0.90[0.85; 0.95] | 46518 | 09.1 | 0.83 [0.79; 0.87] | 45470 | 10.1 | 0.93 [0.89; 0.97] | |||||
| Year of ART initiation | <0.001 | <0.001 | <0.001 | <0.001 | |||||||||||||
| Prior to 2006 | 16937 | 3.7 | 1 | 10896 | 16.4 | 1 | 32059 | 07.6 | 1 | 51484 | 07.5 | 1 | |||||
| 2006 to 2010 | 39970 | 4.2 | 1.51 [1.27; 1.79] | 29114 | 17.9 | 1.10 [1.04; 1.16] | 79803 | 08.4 | 1.08 [1.03; 1.14] | 74682 | 13.0 | 2.34 [2.25; 2.44] | |||||
| 2011 to 2014 | 14376 | 5.7 | 2.23 [1.85; 2.68] | 10365 | 25.7 | 1.61 [1.52; 1.72] | 17485 | 17.1 | 2.65 [2.51; 2.80] | 4118 | 13.5 | 7.22 [6.53; 7.98] | |||||
| Baseline CD4 cell count (Cells/µL) | <0.001 | ||||||||||||||||
| <100 | 16015 | 4.0 | 1 | ||||||||||||||
| 100 to 199 | 13083 | 2.5 | 0.61 [0.53; 0.70] | ||||||||||||||
| 200 to 349 | 13442 | 2.3 | 0.52 [0.46; 0.60] | ||||||||||||||
| 350 to 500 | 4510 | 2.8 | 0.59 [0.48; 0.71] | ||||||||||||||
| ≥500 | 3730 | 4.0 | 0.80 [0.66; 0.96] | ||||||||||||||
| Missing | 20503 | 7.7 | 2.27 [2.05; 2.50] | ||||||||||||||
| Time depending CD4 cell count (Cells/µL) | <0.001 | <0.001 | <0.001 | ||||||||||||||
| <100 | 7283 | 53.1 | 1 | 9820 | 24.6 | 1 | 6134 | 11.1 | 1 | ||||||||
| 100 to 199 | 10576 | 21.1 | 0.56[0.54; 0.59] | 14598 | 15.5 | 0.53 [0.50; 0.56] | 8519 | 11.1 | 0.55 [0.52; 0.59] | ||||||||
| 200 to 349 | 15370 | 13.6 | 0.44 [0.41; 0.46] | 32131 | 09.6 | 0.36 [0.35; 0.38] | 21309 | 10.5 | 0.35 [0.33; 0.37] | ||||||||
| 350 to 500 | 9205 | 8.5 | 0.37 [0.34; 0.40] | 30896 | 06.8 | 0.31 [0.29; 0.33] | 28276 | 12.3 | 0.31 [0.29; 0.33] | ||||||||
| ≥500 | 7940 | 8.6 | 0.38 [0.35; 0.41] | 41903 | 05.4 | 0.29 [0.27; 0.31] | 66046 | 14.0 | 0.31 [0.29; 0.32] | ||||||||
HRa, adjusted cause‐specific Hazard Ratio estimated by Cox regression models; IR/100 PY, incidence rate per 100 person‐years; ORa, adjusted Odd Ratio estimated by the logistic regression model.