Table 4.
Results of Pooled Analysis of Each Polymorphism Based on Five Genetic Models
| TaqI(rs731236) | C vs. T |
CT/CC vs. TT |
CC vs. TT/CT |
CC vs. TT |
CT vs. TT |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p | I2 | OR (95% CI) | p | I2 | OR (95% CI) | p | I2 | OR (95% CI) | p | I2 | OR (95% CI) | p | I2 | ||
| Total (n) | 7 | 1.24 (1.07–1.44) | 0.005 | 42% | 1.45 (0.96–2.19) | 0.08 | 54% | 1.38 (1.03–1.84) | 0.03 | 0% | 0.83 (0.29–2.40) | 0.74 | 75% | 1.41 (0.89–2.22) | 0.14 | 59% |
| Ethnicity | ||||||||||||||||
| Asian | 5 | 1.28 (1.06–1.54) | 0.009 | 60% | 1.67 (0.97–2.87) | 0.06 | 60% | 1.45 (0.93–2.26) | 0.10 | 0% | 1.38 (0.55–3.50) | 0.49 | 0% | 1.67 (0.96–2.90) | 0.07 | 60% |
| Caucasian | 2 | 1.16 (0.90–1.50) | 0.26 | 0% | 1.05 (0.65–1.71) | 0.84 | 5% | 1.33 (0.91–1.95) | 0.14 | 0% | 0.62 (0.13–3.09) | 0.56 | 87% | 0.93 (0.56–1.56) | 0.79 | 29% |
| Dental caries in dentition | ||||||||||||||||
| Deciduous decay | 2 | 1.10 (0.87–1.38) | 0.42 | 0% | 1.39 (0.91–2.15) | 0.13 | 43% | 0.80 (0.05–12.89) | 0.88 | − | 1.28 (0.08–21.28) | 0.87 | − | 1.40 (0.91–2.15) | 0.13 | 44% |
| Mixed caries | 2 | 1.26 (0.87–1.82) | 0.23 | 0% | 1.37 (0.81–2.33) | 0.24 | 0% | 1.23 (0.66–2.29) | 0.51 | 0% | 1.44 (0.72–2.85) | 0.30 | 0% | 1.34 (0.75–2.40) | 0.32 | 0% |
| Permanent tooth caries | 3 | 1.40 (1.11–1.77) | 0.005 | 76% | 1.78 (0.41–7.73) | 0.44 | 89% | 1.44 (1.03–2.00) | 0.03 | 0% | 0.29 (0.16–0.53) | 0.0001 | − | 1.65 (0.33–8.35) | 0.54 | 90% |
p, p value for test of association.
I2 is a measure of heterogeneity expressed in %.
p < 0.05, indicating statistical significance of bold values.
95% CI, 95% confidence interval; OR, odds ratio.