Table 2.

Univariate and multivariate predictors of major vascular complications.

Parameter	Univariate model				Multivariate modela
					SFAR cutpoint >0.75
	OR (95% CI)	p-value	Youden index	Cutpoint	OR (95% CI)	p-value
Age, per 5y	1.02 (0.78–1.3)	0.89	–	–	0.98 (0.72–1.4)	0.91
Female	3.13 (1.1–8.9)	0.03	–	–	3.4 (0.84–14)	0.08
Diabetes	0.51 (0.17–1.6)	0.24	–	–	0.40 (0.12–1.4)	0.15
Tortuosity	2.3 (0.81–5.3)	0.12	–	–	3.1 (1.1–9.2)	0.04
CFA calcification	1.1 (0.45–2.9)	0.77	–	–	1.40 (0.48–4.1)	0.53
BMI	0.95 (0.87–1.0)	0.17	–	–	0.96 (0.86–1.1)	0.46
Creatinine clearance	0.99 (0.96–1.0)	0.41	–	–	1.0 (0.97–1.0)	0.83
PVD	1.18 (0.43–3.2)	0.74	–	–	0.74 (0.23–2.4)	0.62
CAD	4.3 (1.2–15)	0.02	–	–	8.2 (1.8–37)	0.00
Prior CVA	1.05 (0.29–3.8)	0.93	–	–	1.5 (0.36–6.1)	0.59
Prior MI	1.45 (0.56–3.7)	0.44	–	–	0.48 (0.14–1.6)	0.24
CFA diameter, mm	0.65 (0.43–0.99)	0.04	–	–	1.2 (0.51–3.1)	0.63
SEIAR	33 (1.5–794)	0.02	0.310	0.75	0.12 (0.00–459)	0.61
SEIAR > 0.8	2.3 (0.86–6.0)	0.09	–	–	–	–
SFAR	1.2 (0.56–2.3)	0.70	0.311	0.75	–	–
SFAR > 0.8	2.34 (0.89–6.31)	0.08	–	–	–	–
SFAR > 0.72	2.5 (0.94–6.4)	0.06	–	–	–	–
SFAR > 0.75	3.1 (1.2–8.0)	0.01	–	–	3.6 (0.62–21)
EIA MLD, mm	0.63 (0.42–0.93)	0.02	–	–	0.63 (0.21–1.9)	0.42
CFA depth, mm	0.99 (0.97–1.0)	0.53	–	–	1.0 (0.97–1.0)	0.98
CFA Calcification
Maximum Arc	0.24 (0.03–1.9)	0.17	–	–	–	–
Anterior location	2.5 (0.27–23)	0.42	–	–	–	–

Youden Index is sensitivity + specificity − 1.

Abbreviations: CAD: coronary artery disease; MI: myocardial infarction; PVD: peripheral vascular disease; CVA: cerebrovascular accident; SEIAR: sheath to external iliac artery ratio; SFAR: sheath to femoral artery ratio; EIA: external iliac artery; CFA: common femoral artery.

^aSEIAR > 0.75, SFAR > 0.75, Max Arc 91–360° and CFA calcification location are not included in MV model.