Supplementary Table 1.
List of prognosis-related differentially methylated sites.
| Probe | Coef | HR | P.value | Gene symbol |
|---|---|---|---|---|
| cg00311768 | −4.36342 | 0.012735 | 0.047414 | TSTA3 |
| cg00411595 | 9.499339 | 13350.9 | 0.041674 | SLC2A6 |
| cg00666842 | −2.90891 | 0.054535 | 0.016011 | SMYD1 |
| cg00699831 | 24.28987 | 3.54E+10 | 0.015735 | SCD |
| cg01119512 | −11.4891 | 1.02E-05 | 0.044574 | GRHL3 |
| cg01414194 | −4.13226 | 0.016047 | 0.022339 | TSTA3 |
| cg01820374 | 5.957623 | 386.6897 | 0.048866 | LAG3 |
| cg02187231 | 8.532535 | 5077.302 | 0.015247 | VAX2 |
| cg02222728 | 3.95713 | 52.30698 | 0.039254 | SOX17 |
| cg02311932 | 4.740023 | 114.4368 | 0.034187 | RBM24 |
| cg02369775 | 12.83755 | 376076.6 | 0.033092 | IGFBP6 |
| cg02462195 | 3.25937 | 26.03313 | 0.029795 | ADAMTS5 |
| cg03199006 | 45.4402 | 5.43E+19 | 0.002709 | CXCL9 |
| cg03323067 | 4.310195 | 74.455 | 0.034005 | TNS1 |
| cg03709663 | −3.91068 | 0.020027 | 0.029031 | GINS2 |
| cg04370730 | −4.40706 | 0.012191 | 0.034052 | GJB3 |
| cg04454576 | −5.04614 | 0.006434 | 0.009928 | ASCL2 |
| cg04456029 | 13.33355 | 617569.6 | 0.047443 | DTX1 |
| cg04833514 | −4.03234 | 0.017733 | 0.013399 | SLC6A9 |
| cg05008975 | −3.4041 | 0.033237 | 0.047412 | SCN4B |
| cg05526099 | 19.15269 | 2.08E+08 | 0.030173 | CHI3L1 |
| cg05814654 | 3.507149 | 33.35305 | 0.042772 | IL21R |
| cg06195379 | 4.665694 | 106.2393 | 0.046127 | IL32 |
| cg07210669 | −4.59045 | 0.010148 | 0.012612 | S100P |
| cg07712493 | 2.601348 | 13.48189 | 0.027394 | CDO1 |
| cg07747553 | −5.13931 | 0.005862 | 0.049336 | RASD2 |
| cg07763231 | −4.41222 | 0.012128 | 0.021462 | SLC16A3 |
| cg07991704 | −3.3905 | 0.033692 | 0.008325 | SLC4A4 |
| cg08142094 | −4.46022 | 0.01156 | 0.031394 | GINS2 |
| cg08480266 | −3.1528 | 0.042732 | 0.043551 | LGI4 |
| cg08816023 | −3.38711 | 0.033806 | 0.03887 | FGF1 |
| cg09183450 | −5.50468 | 0.004068 | 0.010343 | AHNAK |
| cg09284708 | −5.51481 | 0.004027 | 0.013559 | MOCS1 |
| cg09340386 | −2.32479 | 0.097804 | 0.041455 | TPO |
| cg09757109 | −3.36292 | 0.034634 | 0.037446 | DIXDC1 |
| cg10140583 | −3.92209 | 0.0198 | 0.008001 | LY6D |
| cg10241809 | −6.36823 | 0.001715 | 0.045466 | SLC16A3 |
| cg10270306 | 3.962011 | 52.56294 | 0.042718 | AKAP12 |
| cg10725316 | 2.871826 | 17.66924 | 0.034809 | KCNIP2 |
| cg10846969 | 64.18582 | 7.51E+27 | 0.014242 | CENPW |
| cg10988368 | −5.0549 | 0.006378 | 0.005625 | ASCL2 |
| cg11348249 | 6.264056 | 525.3456 | 0.032164 | AKAP12 |
| cg11580525 | −3.5706 | 0.028139 | 0.045714 | SCN4B |
| cg11644479 | −3.08738 | 0.045621 | 0.035826 | ASCL2 |
| cg12574296 | −3.58437 | 0.027754 | 0.0409 | NCCRP1 |
| cg12989650 | 22.12875 | 4.08E+09 | 0.036625 | ARHGEF15 |
| cg13551227 | 3.624474 | 37.50498 | 0.033813 | KCNIP2 |
| cg13681655 | −4.50336 | 0.011072 | 0.036481 | SDC1 |
| cg13936863 | 7.885756 | 2659.134 | 0.015535 | VAX2 |
| cg13971504 | 12.29604 | 218828.7 | 0.012028 | GCNT4 |
| cg14042396 | −5.03589 | 0.0065 | 0.013656 | MYCN |
| cg14171514 | −3.69861 | 0.024758 | 0.032232 | AHNAK |
| cg14235768 | 5.698774 | 298.5012 | 0.048681 | VAX2 |
| cg14588178 | −3.53185 | 0.029251 | 0.039197 | GDF10 |
| cg15108410 | −3.83748 | 0.021548 | 0.019046 | COL2A1 |
| cg15171154 | −6.35385 | 0.00174 | 0.047176 | TGFBR2 |
| cg15724876 | −4.24938 | 0.014273 | 0.005053 | TGFBR2 |
| cg16350494 | 26.97487 | 5.19E+11 | 0.02856 | FOXP3 |
| cg17306740 | 2.586213 | 13.27938 | 0.047608 | ZBP1 |
| cg17520539 | 5.614495 | 274.3749 | 0.028113 | AKAP12 |
| cg17863139 | −5.8516 | 0.002875 | 0.048414 | LAD1 |
| cg17887364 | −3.66561 | 0.025589 | 0.008412 | EIF4EBP1 |
| cg17967059 | 4.153925 | 63.6835 | 0.04683 | GJB2 |
| cg18183642 | −4.05077 | 0.017409 | 0.014428 | SLC6A9 |
| cg18250832 | −7.23907 | 0.000718 | 0.022473 | NMUR1 |
| cg18438461 | −2.22567 | 0.107995 | 0.044718 | TPO |
| cg18567954 | 13.83816 | 1022913 | 0.027343 | DTX1 |
| cg18825531 | −4.72894 | 0.008836 | 0.042292 | AHNAK |
| cg18967533 | −4.366 | 0.012702 | 0.019672 | KLK6 |
| cg19419246 | −4.16463 | 0.015535 | 0.004675 | FOSB |
| cg19421218 | 7.610693 | 2019.678 | 0.028452 | TIGIT |
| cg19570321 | −3.52385 | 0.029486 | 0.020144 | HRASLS5 |
| cg19699289 | 16.14231 | 10245148 | 0.040794 | VAX2 |
| cg19914554 | 7.227266 | 1376.454 | 0.049081 | CD7 |
| cg20000220 | −3.47643 | 0.030918 | 0.043647 | MAPK15 |
| cg20062691 | −4.74399 | 0.008704 | 0.009959 | ISG15 |
| cg20392764 | −4.67557 | 0.00932 | 0.008544 | ASCL2 |
| cg20518446 | −1.98147 | 0.137866 | 0.048057 | AHNAK |
| cg20914659 | −3.89854 | 0.020271 | 0.018332 | KCNK5 |
| cg20989454 | −4.30745 | 0.013468 | 0.032761 | IRF7 |
| cg21083175 | −3.88221 | 0.020605 | 0.036995 | RCOR2 |
| cg21166775 | −5.21559 | 0.005431 | 0.016962 | RAPGEF3 |
| cg21214613 | −6.40936 | 0.001646 | 0.019865 | HSPB7 |
| cg21234506 | 4.270848 | 71.58232 | 0.004655 | BCL2A1 |
| cg21580376 | 2.54752 | 12.77539 | 0.009966 | ADRB2 |
| cg22077313 | −6.30806 | 0.001822 | 0.019035 | S100P |
| cg22833618 | 7.06031 | 1164.806 | 0.0212 | HRC |
| cg22946658 | −4.78056 | 0.008391 | 0.00482 | ASCL2 |
| cg23492779 | −4.97062 | 0.006939 | 0.012658 | PI16 |
| cg23568324 | −4.31416 | 0.013378 | 0.040389 | TTYH3 |
| cg23588217 | 3.814983 | 45.37598 | 0.036747 | TBX15 |
| cg24617203 | −3.28597 | 0.037404 | 0.01673 | IL1R2 |
| cg25433648 | −4.1992 | 0.015008 | 0.038807 | S100A14 |
| cg25714865 | −2.59033 | 0.074995 | 0.010923 | FSCN1 |
| cg25752754 | −4.47079 | 0.011438 | 0.00175 | SDC1 |
| cg26051413 | −2.60156 | 0.074158 | 0.03539 | ASCL2 |
| cg26584545 | −3.83307 | 0.021643 | 0.017717 | NTN4 |
| cg27146050 | −5.99987 | 0.002479 | 0.040453 | HIF3A |
| cg27245646 | −2.73164 | 0.065113 | 0.032031 | PODXL2 |
| cg27347104 | 19.93238 | 4.53E+08 | 0.043137 | VWF |
| cg27409154 | −4.05648 | 0.01731 | 0.043397 | IGFBP6 |
| cg27450924 | −3.54134 | 0.028974 | 0.023418 | ARL9 |
| ch.1.4190055F | 10.84239 | 51143.43 | 0.028872 | CENPF |
Coef – regression coefficients; HR – hazard ratio.