Table 1. Activity measure of redox enzymes expressed as IU per mg of fresh liver weight (FLW) in each experimental group.
|
Enzyme activity (IU/mg LFW) |
S−P− | S−P+ | S+P − | S+P+ | p-value |
|---|---|---|---|---|---|
| CAT (x106) | 221.6 ± 19.7c | 167.1 ± 9.6a | 228.5 ± 27.0c | 182.4 ± 14.8ab | 0.044 |
| GR | 3.6 ± 0.4a | 3.2 ± 0.4a | 2.4 ± 0.2a | 3.1 ± 0.3a | 0.380 |
| GPX | 5,839.0 ± 1,020.8a | 5,997.9 ± 659.0ab | 9,516.6 ± 1,801.7c | 8,194.9 ± 1,383.5bc | 0.025 |
| Total GST | 223.6 ± 7.9a | 220.6 ± 7.7a | 227.3 ± 6.7a | 230.9 ± 8.3a | 0.454 |
| Total SOD | 3,304.8 ± 179.0a | 3,320.6 ± 67.8a | 3,227.8 ± 71.3a | 3,378.6 ± 199.5a | 0.566 |
| SOD1 | 2,236.3 ± 182.3a | 2,356.1 ± 67.3a | 2,169.1 ± 137.3a | 2,238.2 ± 258.8a | 0.776 |
| SOD2 | 1,068.5 ± 73.3a | 970.3 ± 49.9a | 1,058.6 ± 82.5a | 1,140.4 ± 61.4a | 0.112 |
Notes.
Data are represented as mean ± S.E.M. (n = 3–5/group). Different letters mean significative differences (ANOVA, p ≤ 0.05).
- CAT
- catalase
- GR
- glutathione reductase
- GPX
- glutathione peroxidase
- GST
- glutathione S-transferase
- SOD
- superoxide dismutase
- SOD1
- Cu,Zn-SOD, cytosolic
- SOD2
- Mn-SOD, mitochondrial
- S−P−
- rats neither exposed to stress nor with piracetam treatment
- S−P+
- rats not exposed to stress but treated with piracetam
- S+P−
- rats exposed to stress without piracetam treatment
- S+P+
- rats exposed to stress and treated with piracetam