Table 2.
Blood pressure characteristics of SPRINT (Systolic Blood Pressure Intervention Trial) participants in the ambulatory blood pressure ancillary study by orthostatic hypotension history at the 6-, 12-, or 24-month SPRINT study visit, mean (SD) or %
Variable | Total | Orthostatic hypotension at least once during 6-, 12-, and 24-month visits | No occurrence of orthostatic hypotension |
---|---|---|---|
N = 897 | N = 128 | N = 769 | |
Clinic SBP, mm Hg (27-mo) | 127.6 (15.6) | 129.2 (17.1) | 127.4 (15.3) |
Clinic DBP, mm Hg (27-mo) | 69.7 (12.0) | 69.7 (13.1) | 69.7 (11.8) |
White coat effect, % | 8.3 | 14.8 | 7.2 |
Dipping status, % | |||
Extreme dipper | 10.3 | 3.1 | 11.4 |
Dipper | 35.3 | 28.1 | 36.5 |
Nondipper | 38.8 | 43.8 | 38.0 |
Reverse dipper | 15.6 | 25.0 | 14.0 |
BP phenotypes, % | |||
White coat hypertension | 5.7 | 10.2 | 4.9 |
Masked hypertension | 26.2 | 25.0 | 26.4 |
Controlled hypertension | 51.1 | 48.4 | 51.6 |
Sustained hypertension | 17.0 | 16.4 | 17.1 |
N antihypertensive medications (27-mo) | 2.3 (1.3) | 2.4 (1.3) | 2.3 (1.3) |
24-mo, data collected at 24-month annual visit; 27-mo, data collected at 27-month study visit. Abbreviations: BP, blood pressure; DBP, diastolic blood pressure; N antihypertensive medication, number of antihypertensive medications; SBP, systolic blood pressure. Participant BP phenotypes were defined as follows: (i) white-coat hypertension (clinic BP ≥140/90 mm Hg and daytime ambulatory BP <135/85 mm Hg), (ii) masked hypertension (clinic BP <140/90 mm Hg and daytime ambulatory BP ≥135/85 mm Hg), (iii) controlled hypertension (clinic BP <140/90 mm Hg and daytime ambulatory BP <135/85 mm Hg), and (iv) sustained hypertension (clinic BP ≥140/90 mm Hg and daytime ambulatory BP ≥135/85 mm Hg).