Table 4.
Association of orthostatic hypotension, postural change in SBP and DBP, and orthostatic hypertension (at 6, 12, or 24 months) with ratio of night-to-daytime SBP
| Beta coefficient [95% CI] | Crude | Model 1 | Model 2 |
|---|---|---|---|
| Orthostatic hypotension (6, 12, and 24 months; N = 128) | 0.04 [0.02, 0.06] | 0.04 [0.02, 0.06] | 0.04 [0.02, 0.06] |
| Orthostatic hypotension | |||
| Never (N = 769) | Reference | Reference | Reference |
| Isolated (N = 100) | 0.03 [0.01, 0.05] | 0.03 [0.01, 0.05] | 0.03 [0.01, 0.05] |
| Recurrent (N = 28) | 0.08 [0.05, 0.12] | 0.08 [0.05, 0.12] | 0.08 [0.05, 0.12] |
| Postural change in SBPa (for every −1 mm Hg) | 0.003 [0.002, 0.004] | 0.003 [0.001, 0.004] | 0.003 [0.001, 0.004] |
| Postural change in DBPa (for every −1 mm Hg) | 0.003 [0.002, 0.005] | 0.004 [0.002, 0.005] | 0.004 [0.002, 0.006] |
| Orthostatic hypertension (6, 12, and 24 months; N = 348) | −0.008 [−0.02, 0.008] | −0.013 [−0.03, 0.003] | −0.0013 [−0.03, 0.003] |
| Orthostatic hypertension (6, 12, and 24 months) | |||
| Never (N = 549) | Reference | Reference | Reference |
| Isolated (N = 225) | −0.006 [−0.02, 0.008] | −0.007 [−0.02, 0.007] | −0.005 [−0.01, 0.009] |
| Recurrent (N = 123) | −0.03 [−0.05, −0.01] | −0.03 [−0.05, −0.02] | −0.04 [−0.05, −0.02] |
Model 1: age, sex, and race/ethnicity. Model 2: smoking status (baseline), chronic kidney disease (baseline), chronic kidney disease (24 months), BMI (baseline), HDL (24 months), total cholesterol (24 months), cardiovascular disease (between baseline and 24 months), and treatment group. Abbreviations: BMI, body mass index; BP, blood pressure; CI, confidence interval; DBP, diastolic blood pressure; HDL, high-density lipoprotein; SBP, systolic blood pressure.
aPostural change = average of the difference of standing − seated BP at 6, 12 and 24 months.