Table 3.
Quality of life (PDQ-39SI and EUROHIS-QOL8) and disability (ADLS score) in patients with stages 1C, 1D, 2A, or 2B of the HY-NMSB scale.
| 1C, N = 27 | 1D, N = 15 | 2A, N = 101 | 2B, N = 125 | p a | p b | p c | p d | |
|---|---|---|---|---|---|---|---|---|
| PDQ-39SI | 19.8 ± 11.9 | 28.6 ± 17.1 | 7.9 ± 5.8 | 13.8 ± 9.8 | <0.0001 | <0.0001 | <0.0001 | 0.003 |
| Mobility | 18.1 ± 14.9 | 27.8 ± 17.7 | 6.1 ± 10.5 | 13 ± 16.2 | <0.0001 | 0.001 | <0.0001 | 0.035 |
| Activities of Daily Living | 16.5 ± 15.2 | 28.3 ± 18.3 | 10.9 ± 12.4 | 15.9 ± 16.1 | <0.0001 | 0.007 | 0.056 | 0.710 |
| Emotional well-being | 28.7 ± 16.4 | 35.5 ± 21.3 | 8.9 ± 9.4 | 14.9 ± 13.7 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
| Stigma | 16.4 ± 20.4 | 23.8 ± 23.9 | 8.4 ± 15.7 | 13.9 ± 19.9 | 0.013 | 0.140 | 0.030 | 0.448 |
| Social support | 13.6 ± 17.8 | 19.4 ± 22.6 | 2.4 ± 9.9 | 5.3 ± 13.8 | <0.0001 | 0.003 | <0.0001 | 0.005 |
| Cognition | 21.9 ± 17.4 | 32.5 ± 18.8 | 8.3 ± 9.6 | 15.9 ± 13.7 | <0.0001 | 0.001 | <0.0001 | 0.099 |
| Communication | 14.2 ± 15.9 | 20.6 ± 19.6 | 4.1 ± 8.4 | 7.9 ± 12.1 | <0.0001 | 0.007 | <0.0001 | 0.026 |
| Pain and discomfort | 27.8 ± 20.1 | 38.3 ± 27.4 | 13.5 ± 13.5 | 21.2 ± 20.3 | <0.0001 | 0.010 | <0.0001 | 0.053 |
| PQ-10 | 6.9 ± 1.6 | 6.4 ± 1.5 | 7.9 ± 1.2 | 7.5 ± 1.5 | <0.0001 | 0.008 | 0.008 | 0.201 |
| EUROHIS-QOL8 | 3.6 ± 0.5 | 3.5 ± 0.4 | 4.1 ± 0.4 | 3.9 ± 0.5 | <0.0001 | 0.004 | <0.0001 | 0.030 |
| Quality of life | 3.6 ± 0.6 | 3.2 ± 0.6 | 4.1 ± 0.6 | 3.9 ± 0.6 | <0.0001 | <0.0001 | 0.001 | 0.048 |
| Health status | 3.2 ± 0.9 | 3.2 ± 0.6 | 3.6 ± 0.7 | 3.3 ± 0.8 | 0.014 | 0.726 | 0.051 | 0.888 |
| Energy | 3.4 ± 0.7 | 3.4 ± 0.6 | 4.1 ± 0.6 | 3.8 ± 0.7 | <0.0001 | 0.025 | <0.0001 | 0.009 |
| Autonomy for ADL | 3.5 ± 0.7 | 3.5 ± 0.5 | 4.1 ± 0.6 | 3.7 ± 0.7 | <0.0001 | 0.065 | <0.0001 | 0.089 |
| Self-esteem | 3.6 ± 0.8 | 3.5 ± 0.6 | 4.2 ± 0.6 | 3.9 ± 0.7 | <0.0001 | 0.015 | <0.0001 | 0.016 |
| Social relationships | 3.9 ± 0.6 | 3.8 ± 0.6 | 4.4 ± 0.6 | 4.2 ± 0.6 | 0.001 | 0.023 | <0.0001 | 0.022 |
| Economic capacity | 3.7 ± 0.7 | 3.4 ± 0.7 | 3.9 ± 0.8 | 3.9 ± 0.6 | 0.010 | 0.025 | 0.014 | 0.054 |
| Habitat | 3.9 ± 0.8 | 3.9 ± 0.7 | 4.4 ± 0.6 | 4.3 ± 0.6 | 0.005 | 0.001 | 0.160 | 0.114 |
| ADLS score | 92.6 ± 7.1 | 88 ± 6.8 | 91.8 ± 5.9 | 89.5 ± 8 | 0.025 | 0.246 | 0.461 | 0.061 |
| FD (%) | 0 | 0 | 1 | 4 | 0.871 | 0.562 | 0.789 | 0.371 |
Chi-squared and Mann–Whitney–Wilcoxon test were applied. The results represent percentages or mean ± SD; pa, 1D vs 2A; pb, 1D vs 2B; pc, 1C vs 2A; pd, 1C vs 2B. ADLS, Schwab and England Activities of Daily Living Scale; EUROHIS-QOL8, EUROHIS-QOL 8-item index; PDQ-39SI, 39-item Parkinson's Disease Quality of Life Questionnaire Summary Index.