Table 4.
Quality of life (PDQ-39SI and EUROHIS-QOL8) and disability (ADLS score) in patients with stages 2C, 2D, 3A, or 3B of the HY-NMSB scale.
| 2C, N = 93 | 2D, N = 91 | 3A, N = 6 | 3B, N = 9 | p a | p b | p c | p d | |
|---|---|---|---|---|---|---|---|---|
| PDQ-39SI | 18.5 ± 10.2 | 31.8 ± 13.8 | 14.2 ± 10.9 | 21.5 ± 7.9 | 0.003 | 0.029 | 0.173 | 0.238 |
| Mobility | 17.2 ± 14.9 | 32 ± 2.1 | 27.1 ± 31.2 | 27.5 ± 16.3 | 0.372 | 0.722 | 0.713 | 0.048 |
| Activities of Daily Living | 18.4 ± 16.4 | 31.1 ± 23.3 | 6.9 ± 7.7 | 25.9 ± 11.7 | 0.005 | 0.722 | 0.081 | 0.084 |
| Emotional well-being | 25.6 ± 20.1 | 41.7 ± 23.1 | 15.9 ± 20.8 | 24.5 ± 19.5 | 0.014 | 0.036 | 0.203 | 0.953 |
| Stigma | 9.3 ± 15.1 | 22.4 ± 24.4 | 7.3 ± 15 | 6.9 ± 14.1 | 0.109 | 0.073 | 0.636 | 0.749 |
| Social support | 9.9 ± 16.7 | 19.1 ± 21.9 | 0 ± 0 | 2.8 ± 4.2 | 0.015 | 0.048 | 0.081 | 0.526 |
| Cognition | 24.4 ± 15.9 | 35.7 ± 21.2 | 1 ± 2.6 | 24.3 ± 13.4 | <0.0001 | 0.109 | <0.0001 | 0.948 |
| Communication | 9.5 ± 13.6 | 18.4 ± 18.7 | 2.8 ± 6.8 | 13.9 ± 13.8 | 0.025 | 0.633 | 0.183 | 0.226 |
| Pain and discomfort | 30.9 ± 19.6 | 46.1 ± 24.6 | 34.7 ± 22.6 | 28.7 ± 19.6 | 0.209 | 0.031 | 0.830 | 0.673 |
| PQ-10 | 7 ± 1.4 | 6.2 ± 1.6 | 8.5 ± 1.5 | 7.2 ± 1.3 | 0.003 | 0.069 | 0.025 | 0.620 |
| EUROHIS-QOL8 | 3.7 ± 0.4 | 3.3 ± 0.6 | 3.8 ± 0.6 | 3.6 ± 0.4 | 0.048 | 0.169 | 0.590 | 0.377 |
| Quality of life | 3.7 ± 0.7 | 3.4 ± 0.7 | 4 ± 0.9 | 3.6 ± 0.5 | 0.108 | 0.563 | 0.462 | 0.328 |
| Health status | 3 ± 0.7 | 2.6 ± 0.9 | 3.2 ± 0.7 | 2.7 ± 0.5 | 0.134 | 0.774 | 0.598 | 0.139 |
| Energy | 3.7 ± 0.7 | 3.2 ± 0.9 | 3.8 ± 0.4 | 3.6 ± 0.5 | 0.078 | 0.293 | 0.553 | 0.544 |
| Autonomy for ADL | 3.4 ± 0.7 | 3 ± 0.9 | 3 ± 0.6 | 3.2 ± 0.7 | 0.819 | 0.625 | 0.124 | 0.340 |
| Self-esteem | 3.6 ± 0.7 | 3.2 ± 0.9 | 4 ± 0.9 | 3.8 ± 0.7 | 0.083 | 0.112 | 0.335 | 0.696 |
| Social relationships | 4 ± 0.7 | 3.6 ± 0.8 | 4 ± 0.7 | 3.9 ± 0.6 | 0.115 | 0.322 | 0.649 | 0.520 |
| Economic capacity | 3.9 ± 0.7 | 3.5 ± 0.9 | 4.2 ± 0.7 | 3.8 ± 1.1 | 0.064 | 0.231 | 0.311 | 0.855 |
| Habitat | 4.3 ± 0.6 | 3.9 ± 0.7 | 4.2 ± 0.7 | 4.1 ± 0.9 | 0.369 | 0.255 | 0.713 | 0.751 |
| ADLS score | 86.5 ± 9.3 | 81.8 ± 11.5 | 90 ± 8.9 | 83.3 ± 10 | 0.091 | 0.769 | 0.421 | 0.278 |
| FD (%) | 9.7 | 25.3 | 0 | 22.2 | 0.187 | 0.601 | 0.556 | 0.250 |
Chi-squared and Mann–Whitney–Wilcoxon test were applied. The results represent percentages or mean ± SD; pa, 2D vs 3A; pb, 2D vs 3B; pc, 2C vs 3A; pd, 2C vs 3B. ADLS, Schwab and England Activities of Daily Living Scale; EUROHIS-QOL8, EUROHIS-QOL 8-item index; PDQ-39SI, 39-item Parkinson's Disease Quality of Life Questionnaire Summary Index.