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. 2021 May 18;16:3473–3485. doi: 10.2147/IJN.S301470

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© 2021 da Silva Brum et al.

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Photomicrographs of slides stained with Masson’s trichrome. The bluish color indicates collagen fibrils in the bone matrix. (A) bone defects filled with hydroxyapatite; (B) bone defects filled with nano-hydroxyapatite/ß tricalcium phosphate; (C) unfilled (control). Scale bar 100 µm, X 400 magnification.