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. 2021 May 18;16:3429–3456. doi: 10.2147/IJN.S303412

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© 2021 Marycz et al.

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The pro-osteogenic impact of the nanocomposites alone and in combination with the miR21/124 evaluated without the magnetic field influence (MF-) and under magnetic field (MF+). The evaluated parameters were matrix mineralization (A and B) and Coll-1 (C) gene expression in MC3T3-E1 cell line. Significant differences are indicated as follows (*p<0,005, **p<0,001, ***p<0,001 and ****p<0.0001) and non-significant are marked as ns. The comparisons between groups are marked with brackets. The black symbols refer to the differences between CTRL and nHAp/IO groups, while red symbols are for nHAp/IO and nHAp/IO@miR-21/124 groups.