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. Author manuscript; available in PMC: 2021 Aug 23.
Published in final edited form as: Lab Invest. 2021 Feb 23;101(6):785–793. doi: 10.1038/s41374-020-00506-0

Figure 2). Treg marker expression is higher in Basal-like tumors.

Figure 2)

(a) T regulatory (Treg) signatures were higher in Basal-like tumors compared to Luminal A tumors only in epithelium-enriched (p = 0.02) areas but not in immune-high regions (p = 0.86). (b) Higher Treg signature expression in Basal-like tumors in tissue microarrays (TMAs) (p = 0.0078). (c) Receiver operating characteristic (ROC) analysis shows 92.9% sensitivity in Basal-like versus Luminal A classification based on Treg signature expression. (d) Significant differences in immune marker expression between Luminal A and Basal-like tumors in TMAs. Volcano plot of Basal-like versus Luminal A. Data points are represented as black dots with annotation for markers with q < 0.05 and fold change > 2. Dashed lines indicate the cut off q < 0.05 and fold change < 2.