Table 3.
Carotid-IMT Measure | Model a | Estimate (95% CI) | P-Value for Pairwise Difference | ||||
---|---|---|---|---|---|---|---|
Segment 1 | Segment 2 | Segment 3 | Segment 1 vs. 2 | Segment 1 vs. 3 | Segment 2 vs. 3 | ||
Average Carotid Artery IMT | 1 | 0.59 (−0.04 to 1.23) | 0.88 (0.20 to 1.56) | 0.94 (0.39 to 1.49) | 0.49 | 0.40 | 0.88 |
2 | 0.52 (−0.07 to 1.12) | 0.86 (0.21 to 1.51) | 0.72 (0.19 to 1.26) | 0.39 | 0.60 | 0.72 | |
3 | 0.08 (−0.62 to 0.79) | 0.41 (−0.37 to 1.19) | 0.25 (−0.43 to 0.95) | 0.44 | 0.68 | 0.70 | |
Common Carotid Artery IMT | 1 | 0.98 (0.32 to 1.64) | 0.79 (0.08 to 1.51) | 0.79 (0.24 to 1.35) | 0.67 | 0.66 | 1.00 |
2 | 0.85 (0.22 to 1.48) | 0.69 (0.01 to 1.38) | 0.54 (0.01 to 1.08) | 0.71 | 0.44 | 0.70 | |
3 | 0.21 (−0.50 to 0.93) | 0.16 (−0.64 to 0.96) | −0.19 (−0.87 to 0.49) | 0.90 | 0.33 | 0.41 | |
Internal Carotid Artery IMT | 1 | 0.54 (−0.47 to 1.55) | 1.95 (0.83 to 3.07) | 1.08 (0.22 to 1.95) | 0.04 | 0.41 | 0.18 |
2 | 0.52 (−0.44 to 1.50) | 2.06 (0.98 to 3.16) | 1.01 (0.17 to 1.85) | 0.02 | 0.44 | 0.10 | |
3 | −0.01 (−1.13 to 1.11) | 1.60 (0.33 to 2.87) | 0.60 (−0.48 to 1.69) | 0.02 | 0.34 | 0.13 |
Model 1: main effects of VAT and time segment indicator and their interaction. Model 2: model 1 + age, race, and study site. Model 3: model 2 + smoking, systolic blood pressure, low-density lipoprotein cholesterol, diabetes, and body-mass index.
Bolded estimates indicate P-value < 0.05.
IMT = intima-media thickness; VAT = visceral adipose tissue.