Fig. 2.

The protective effect of SES against CYL-induced cytotoxicity in normal lung cells. A The morphological change induced by CYL in WI-38 cells and A549 cells; (a) Control group; (b) CYL-treated group; (c) SES + CYL- treated group. B The effect of CYL on nuclear condensation in WI-38 cells observed by fluorescence microscope using DAPI staining; (a) Control group; (b) CYL-treated group; (c) SES + CYL- treated group. C The percentage of cell viability by trypan exclusion test showing the protective effect of SES against CYL-induced cell death in WI-38 cells. The experiments were performed independently in triplicates and data are expressed as Mean ± S.D. (n = 3), *p < 0.05 when compared with control group. #p < 0.05 when compared with CYL group. CYL cyclophosphamide, SES sesamol