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. Author manuscript; available in PMC: 2021 May 23.
Published in final edited form as: Chembiochem. 2018 Dec 13;20(3):360–365. doi: 10.1002/cbic.201800651

Scheme 1.

Scheme 1.

Synthesis of diaryl tetrazoles used in this study. (a) EtOH, reflux, 4 h, 95%. (b) Pyridine, 0 °C to rt, 24 h, 63%. (c) 2-azidoethylene diamine, HBTU, NMM, DMF, rt, 2 h, 91%. (d) CuI, DCM, reflux, 72h, 45%.