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. 2021 May 22;21:273. doi: 10.1186/s12935-021-01984-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Circ_0006168 expression was increased in ESCC tissues, ESCC cells, and Taxol-resistant cells. A The expression level of circ_0006168 in ESCC tissues (n = 40) and adjacent normal tissues (n = 40) was detected by qRT-PCR. B The abundance of circ_0006168 in ESCC cells (Eca109, KYSE450, KYSE150, and KYSE30) and HET-1A cells was analyzed by qRT-PCR. C Circ_0006168 level was examined by qRT-PCR in HET-1A, Eca109, KYSE150 cells, Eca109/Taxol, and KYSE150/Taxol cells. D The expression levels of circ_0006168 and linear CNOT6L were determined after treatment of RNase R by qRT-PCR. **P < 0.001, ***P < 0.0001