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. 2021 May 22;20:52. doi: 10.1186/s12944-021-01480-2

Table 3.

Univariate multinomial regression analysis of risk factors for benign breast disease and breast cancer in relation to controls

Variable Categories Benign Breast Disease P value Breast cancer P-value
OR (95% CI) OR (95% CI)
Age (years) ≥ 50 1.38 (0.63–3.03) 0.424 1.62 (0.74–3.57) 0.231
<  50 Ref Ref
Menarche age (years) <  12 1.39 (0.45–4.37) 0.566 1.39 (0.48–4.37) 0.566
≥ 12 Ref Ref
Menopause age (years) >  46 0.84 (0.33–2.15) 0.716 1.65 (0.67–4.09) 0.280
≤ 46 Ref Ref
BMI (kg/m2) ≥ 23 1.69 (0.74–3.86) 0.213 114.33 (14.42–906.25) < 0.001
18.5- < 23 Ref Ref
Total cholesterol (mg/dL) ≥ 200 1.09 (0.47–2.56) 0.829 8.27 (3.35–20.38) < 0.001
< 200 Ref Ref
Low density lipoprotein (mg/ dL) ≥ 130 1.27 (0.57–2.79) 0.548 5.79 (2.33–14.44) < 0.001
<  130 Ref Ref
High-density lipoprotein (mg/ dL) <  40 0.92 (0.41–2.05) 0.838 2.44 (1.09–5.47) 0.029
≥ 40 Ref Ref
Triglyceride (mg/ dL) ≥ 150 1.15 (0.41–3.28) 0.790 5.69 (2.23–14.53) < 0.001
<  150 Ref Ref

Data expressed as n(%) and mean ± SD where appropriate; OR Odds Ratio

* P-value significant at < 0.05 level in comparison to control and benign breast disease